ISSN 2079-3537      

 
 
 
                                                                                                                                                                                                                                                                                                                                                                                                                                                                             





Scientific Visualization, 2021, volume 13, number 3, pages 58 - 65, DOI: 10.26583/sv.13.3.06

Study of The Cold Test Effect on Microcirculation by Video Capillaroscopy

Authors: M.V. Volkov1,A, A.S. Machikhin2,B, E.D. Lovchikova3,B,C, D.D. Khokhlov4,B, I.A. Balandin5,B, A.V. Potemkin6,A, V.S. Galanova7,B,C, I.V. Danilycheva8,D, I.V. Dorofeeva9,D

A University ITMO

B Scientific and Technological Center of Unique Instrumentation RAS

C Bauman Moscow State Technical University

D Institute of Immunology FMBA

1 ORCID: 0000-0002-9658-9467, ph-m.volkov@yandex.ru

2 ORCID: 0000-0002-2864-3214, machikhin@ntcup.ru

3 ORCID: 0000-0002-8024-1028, kat.lovchikova@yandex.ru

4 ORCID: 0000-0003-0919-7762, khokhlov.dd@ntcup.ru

5 ORCID: 0000-0003-2120-0186, bia5310@yandex.ru

6 ORCID: 0000-0002-9838-2267, appanpotemkin@gmail.com

7 ORCID: 0000-0002-9070-8568, victoriagalanova@icloud.com

8 ORCID: 0000-0002-8279-2173, ivdanilycheva@mail.ru

9 ORCID: 0000-0002-4423-1797, idorofeeva1@gmail.com

 

Abstract

The cold stress is one of the main functional tests in the study of the microvascular bed of the skin. An important task is to automate visualization of the capillary network and measurement of microcirculation parameters directly in the local area of inflammation. In this paper, we describe a system developed for non-invasive visualization of the microcirculation and the processing of such images in order to determine the morphological parameters of the capillary network and their changes under external conditions. Proposed approach provides high-quality visualization of the skin microvessels and allows obtaining reliable information about the capillary map. The results of experimental studies are presented. Obtained data may be used for the development of the new methods for detecting hidden hemodynamic disorders and diagnostics of various diseases.

 

Keywords: capillaroscopy, computational imaging, microcirculation visualization, non-destructive diagnosis.